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Owing to prenatal ultrasound technology, there has been an immense acceleration in understanding of early human development. Recent advanced three-dimensional (3D) technology has produced exciting new applications of high-definition live (HDlive) silhouette and HDliveFlow imaging. By HDlive silhouette mode, an inner cystic structure with fluid collection can be depicted through the outer surface structure of the body and it can be appropriately named as ‘see-through fashion’. Additionally, HDlive silhouette can depict hyperechoic structures, such as bones because skeletal system is demonstrated by ultrasound as conspicuously echogenic organs. HDliveFlow imaging adds more spatial resolution to conventional 3D ultrasound angiogram. HDliveFlow imaging demonstrates fine peripheral blood vessels, such as vascularity of the lung, brain and eyeballs. HDliveFlow combined with silhouette mode demonstrates the accurate location of vascularity inside organs. Simultaneous visualization of both structure and vascularity is quite comprehensive and may add further clinical information of vascularization. Thus, ‘see-through fashion’ imaging technology provides us comprehensive orientation and persuasive localization of inner morphological structure as well as of angiostructure inside the fetal organs. HDlive silhouette and flow imaging add further clinical significance to conventional three/four-dimensional (3D/4D) imaging in fields of sonoembryology and neurosonology, and may open up a new field of sono-ophthalmology. Owing to novel applications with clinical significance, fetal ultrasound is at present noninvasive, direct-viewing of the embryo/fetus, and all-inclusive technology, and is definitely the first modality of prenatal diagnosis with infinite potential.

Novel Application of HDlive Silhouette and HDliveFlow: Clinical Significance of the ‘See-through Fashion’ in Prenatal Diagnosis