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Background: Placental maturity assessed by ultrasound has been classified into 3 grades by Grannum. Grade 3 before the 36th week of pregnancy is associated with adverse maternofetal morbidity. We sought to determine the prevalence of grade 3 placenta between the 34th and the 36th week of pregnancy and to assess its impact on maternofetal outcomes in Cameroon. Materials and methods: This prospective cohort study was conducted from January 2012 to July 2013 in the maternity unit of the Yaoundé Central Hospital. Results: One hundred and two women with singleton preg nancies between the 34th and 36th weeks were included. Grade 3 placenta accounted for 5.9% of our sample. Grade 3 was significantly associated with the following: anterior location of the placenta (RR = 5.36; 95% CI: 1.36–9.62; p = 0.03), pre-eclampsia (RR = 12; 95% CI: 3.52–20.8; p = 0,003), meconium-stained amniotic fluid (RR = 4.32; 95% CI: 1.65–11.51; p = 0.04) and intrauterine growth restriction (RR = 2.43; 95% CI: 1.33–15.6; p = 0.007). Conclusion: Grade 3 placental maturity before the 36th week of pregnancy is significantly associated with some maternal and fetal morbidities. Therefore, it warrants close monitoring to detect and avoid complications. ORIGINAL ARtIcLe 1Obstetrician and Gynecologist, Senior Lecturer, 2Obstetrician and Gynecologist, Lecturer, 3Resident, 4Student 1Department of Obstetrics and Gynecology, Unit of the Yaoundé Central Hospital; Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences University of Yaoundé I, Cameroon 31186 Yaoundé, Cameroon 2Department of Obstetrics and Gynecology, Unit of the Yaoundé Central Hospital; Department of Obstetrics and gynecology, Higher Institute of Medical Technology of Nkolondom, YaoundéCameroon; Research, Education and Health Development Associates Group, Dschang, Cameroon 3Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon 4Department of Obstetrics and Gynecology, Higher Institute of Health Sciences ‘Université des Montagnes’, Bangangté, Cameroon Corresponding Author: Jeanne Hortence Fouedjio, Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Unit of the Yaoundé Central Hospital; Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences University of Yaoundé I, Cameroon 31186 Yaoundé, Cameroon, Phone: 00237696818339, e-mail: fouedjiojeanne@yahoo.fr

donald school journal of ultrasound in obstetrics and gynecology

Associations between the Grade of Placental Maturity at Third Trimester Ultrasound and Maternofetal Outcomes at the Maternity of the Yaoundé Central Hospital: A Prospective Cohort Study