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A 56-year-old female patient with the phenotype of Albrights hereditary osteodystrophy (AHO) and pseudohypoparathyroidism 1a (PHP)diagnosed in 1987 was shown to have a heterozygote inactivating mutation on the GNAS1 gene. The patient has been treated with oralcalcium and vitamin D since diagnosis of PHP 1a and developed primary hyperparathyroidism (pHPT) in 2009. Ultrasound as well as 99Tcsestamibicould demonstrate a lesion in the right lower position. Intraoperatively, a solitary parathyroid adenoma was found and resectedleading to a normalization' of PTH and calcium. This case highlight is the rare coincidence of PHP, AHO and pHPT.

Overlap of Pseudohypoparathyroidism and Primary Hyperparathyroidism in a Patient: Just a Coincidence?