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Recent advances in molecular biology have provided insight into the complex network of interaction that occurs within the immune system. The use of specific Immunomodulators to strengthen a deficient immune system or bolster a normal immune system presents a unique strategy for the treatment of various disorders that will clearly affect the practice of clinical medicine for many years to come. A major difficulty limiting the use of immunomodulators in clinical medicine has been the complexity of the immunoregulatory network in which modulation of one component usually perturbs the entire system, thus diminishing the specificity of the approach. Several immunomodulators are currently being tested in the treatment of the immune defect of the acquired immunodeficiency syndrome. This article covers the types of immunomodulators, their mechanism of action and their applications.

Rationale in Usage of Immunomodulators for Management of Head, Face and Neck Cancers