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Enteric fever is classically caused by S. Typhi & S. Paratyphi A, B & C and it is known to be endemic in India. For optimal patient care, precise information on antibiotic susceptibility pattern is required. Hence, this study was undertaken to know the antimicrobial sensitivity profile of Salmonella serotypes isolated from blood in a tertiary care hospital of Punjab. All the blood samples received from January 2010 – December 2011 were processed by automated blood culture systems (BACTEC 9240/BacT-Alert 3D). Identification and antimicrobial susceptibility pattern of Salmonella strains was studied by automated identification system (MicroScan Walk-Away/ VITEK 2). Out of a total of 35854 blood samples, 5234 (14.6%) samples were found to be positive for bacterial growth, of which 363 (6.93%) were Salmonella spp. Of these, 281 (77.4%) were S. Typhi and 82 (22.6%) were S. Paratyphi A. Only 2 (0.7%) isolates of S. Typhi were found resistant to ampicillin and trimethoprim-sulfamethoxazole, and 5 (1.8%) were resistant to ciprofloxacin & levofloxacin. All the S. Typhi isolates were sensitive to 3rd generation cephalosporins. S. Paratyphi A isolates were sensitive (100%) to all the drugs, except trimethoprim-sulphamethoxazole (97.6%) & ceftriaxone (98.8%). Though multi drug resistant Salmonella are being reported from various parts of India, in our region the Salmonella isolates are still susceptible to the commonly used drugs.

Sensitivity pattern of Salmonella serotypes from a tertiary care hospital of Punjab