English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

This study is aimed to correlate apparent diffusion coefficient (ADC) values and clinical T-stage, serum PSA, pathology Gleason scores. We also further analyzed whether ADC values could be used to appropriately define the risk groups. 135 biopsy-proven, radiotherapy-(RT)-treated, prostate cancer patients who underwent pre-RT DW-MRI and standard T2W pelvic MRI were included. ADC and normalized ADC (nADC) values were calculated from DW-MRI delivered a median 8.1 weeks after prostate biopsy. ADC values were correlated with clinical risk factor values by using Pearson correlation test. ADCs in low-, intermediate-, and high-risk patients were 0.873±0.122X10–3 mm2/s, 0.763±0.124X10–3 mm2/s, and 0.701±0.132X10–3 mm2/s (p= 0.001), respectively. Patients with preRT PSA <10 ng/mL had significantly higher ADCs than patients with preRT PSA 10–20 ng/mL (p= 0.02) or >20 ng/mL (p< 0.001). Mean ADC for patients with Gleason score <7 was significantly higher than patients scoring 7 (p= 0.001) or >7 (p < 0.001). Clinical stage <T2b patients had significantly higher ADC values versus stage T2b (p=0.001) and T2b tumors (p< 0.001). ADC demonstrated stronger correlation with NCCN risk groups (R=–0.510; p< 0.001). All clinical factors except Gleason score had moderate inverse correlation with nADC. Best nADC correlation occurred with NCCN risk groups (R=-0.461; p< 0.001). ADCs measured by DW-MRI are noninvasive prognostic markers of clinical parameters and risk for prostate cancer in RT candidates.

uhod : uluslararası hematoloji - onkoloji dergisi

Correlation of Clinical Risk Factors with Diffusion-Weighted Magnetic Resonance Images in Prostate Cancer Patients Treated with Definitive Radiotherapy