English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This meta-analysis will be performed to evaluate the safety and efficacy of biweekly CPT-11 plus CDDP versus CPT11 alone in patients with advanced gastric cancer (AGC) who had received S-1–based first-line chemotherapy. Individual patient–level data from two prospective randomized trials employing the same regimens in the second-line setting for advanced or recurrent gastric cancer will be collected for the study. The primary endpoint is overall survival. Subset analysis will be performed to identify differences in 1) cases with metastatic progression or early relapse after adjuvant chemotherapy, 2) previous platinum therapy, and 3) histological intestinal or diffuse type. Cumulative data from 298 patients will help define a better regimen for S-1 failure cases and might give an important information in selecting a more suitable regimen for subsets of patients.

annals of cancer research and therapy

Meta-analysis of patient-level data on biweekly irinotecan plus cisplatin versus irinotecan alone as second-line treatment for advanced gastric cancer with the TCOG GI-0801 BIRIP and ECRIN TRICS RCTs: protocol paper