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The study was conducted to analyze the chemical constituent and to evaluate the antimicrobial properties of the leaf essential oil of Gossypium hirsutum. The oil was obtained by hydrodistillation and was analyzed by gas chromatography and gas chromatography-mass spectrometry (GC/GC-MS). This revealed the presence of fifty components accounting for - % of the total oil fraction. The leaf oil was dominated by patchoulane (14.70%), Ally 1-2, 6,6–trimethyl bicyclo (3.1.1) heptane (5.95%). 1,7, 7 – trimethyl bicyclo (2.2.1) heptanes (5.95%)and 9- (1 – methylethylidene) bicyclo (6.1.0) nonane (5.95%). The oil displayed high antimicrobial potentials to some tested microorganisms.

CHEMICAL COMPOSITIONS AND ANTIMICROBIAL ACTIVITY OF THE LEAF ESSENTIAL OIL OF GOSSYPIUM HIRSUTUM