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Purpose: This study conducts an in vitro comparison of the depth of penetration of a resin infiltrant material (Icon), a two-step self-etch resin-based material (OptiBond TM XTR), and a solvent-free self-etch resin-based material (Bond-1SF) into white spot lesions (WSLs). Methodology: Through an in vitro clinical trial, a total of 60 human posterior teeth, free from caries, were collected. The buccal and lingual surfaces of each tooth were marked, resulting in a total of 120 samples of surfaces, which represented the operational sample size. The samples were randomly divided into four equal main groups (n = 30) according to the materials used. Group 1 (M1) was the control group. Group 2 (M2) was restored using Icon, Group 3 (M3) using OptiBond TM XTR, and Group 4 (M4) using Bond-1SF. Each group was divided into two equal groups (n = 15) according to the surface treatment, and the first group (W1) was subjected to surface treatment but the second group (W2) was not. The resin penetration depth was observed using confocal laser scanning microscopy. Findings: The highest penetration depth was recorded for Group 2 with surface treatment (M2W1), and the lowest was recorded for Group 4 without surface treatment (M4W2). An analysis of variance test revealed a statistically significant difference in the penetration depth of tested materials ( p < 0.05). Conclusion: Icon shows the best penetration depth value in relation to WSLs, whereas Bond-1SF shows the worst. Surface treatment has a positive effect on the penetration depth of the resin-based materials.

A COMPARATIVE STUDY IN PENETRATION DEPTH OF RESIN-BASED MATERIALS INTO WHITE SPOT LESION