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This study was aimed at assessing NK cell cytotoxicity, soluble Fas ligand (sFasL) serum concentration among Toxoplasmosis patients, and healthy controls. To understanding the role of these parameters in the immunity and pathophysiology of toxoplasmosis, correlations between these parameters were evaluated. NK cell cytotoxicity was estimated by the cultivation of Candida cells on Sabouraud`s dextrose agar (SDA) plate which had been incubated for two hours with NK cells. Colony-forming inhibition assay (CFIA) by calculating anticandidal index (ACI) has been estimated in two ratios of target: effector (T: E) cells 1:3 (NK R1) and 1:30 (NK R2) for both patients and controls. Enzyme-linked immunosorbent assay (ELISA) kit sFasL were used to estimate serum level in both patients and controls. There is a decrease in sFasL in toxoplasmosis compared to controls.

Impact of toxoplasmosis on apoptotic activity and natural killer cell cytotoxicity among Iraqi pregnant women