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Objective: To identify the caloric and protein adequacy of enteral nutritional therapy (ENT) and evaluate the relationship with gastrointestinal complications and intercurrences in critically ill patients. Method: This is an observational, analytical and prospective study carried out in two intensive care units of a public emergency and emergency hospital. A survey of demographic, clinical and nutritional data of patients using exclusive enteral nutritional therapy for 15 days was performed. The caloric and protein adequacy was defined in two categories: ≥80% and ≥100%. The Shapiro Wilk test was used for analysis of normality and Test Denise Peixoto Silva, Nágila Araújo de Carvalho, Larissa Silva Barbosa | Adequação da terapia nutricional enteral, complicações gastrointestinais e intercorrências em pacientes críticos R. Assoc. bras. Nutr. 2021; 12 (1): 104-115 ISSN 2357-7894 105 T and Mann Whitney for comparison of the protein and calorie mean values prescribed and received, as well as the comparison of the days of caloric and protein inadequacy with a significance of 5%. Results: A total of 67 patients were evaluated, of which 52.2% and 22.4% achieved adequacy ≥ 80% and ≥ 100% for calories, as well as 37.3% and 10.4% for protein, respectively. Constipation was the most present complication, followed by vomiting, diarrhea and exit of enteral catheter (EC). The variables HR> 500 mL, vomiting, EC obstruction and ENT interruption when evaluated with the days of inadequacy of 80 and 100% for calories and proteins were significant. Conclusion: There was inadequacy of the calories and proteins prescribed and received in relation to the estimated needs. Patients who presented EC> 500ml, vomiting, EC obstruction and interruption of ENT had more days of caloric and protein inadequacy.