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Background: The COVID-19 pandemic has various unfavorable effects on individuals and the community. This study aims to assess the psychological impact of the COVID-19 epidemic and the subsequent social isolation on the general population of Karnataka, India. Methods: A web-based cross-sectional survey was conducted in Karnataka from 8 to 14 April 2020 using the snowball technique. The psychological impact was assessed with the help of the nine-item Patient Health Questionnaire-9 (PHQ-9) and seven-item General Anxiety Disorder-7 (GAD-7) questionnaires. IBM SPSS Statistics Subscription version 16.0 was recruited to analyze the data. Descriptive (Mean + Standard Deviation) and bivariate (Pearson chi-square and ANOVA tests) analysis used to present data with the significance level set at less than 0.05. Results: This study included 1537 participants from 26 cities in Karnataka. About two-thirds of the respondents were undergraduate students (951, 61.9%), females (768, 50.0%), and 40.1% stayed about 15-20 days in social isolation. The prevalence of depression was 47.0%, and anxiety was 41.5%, respectively, among the surveyed sample. After the analysis, the age group 21-30 year old (P < 0.001), females P < 0.001), urban residents (P = 0.021), and the students (P p < 0.001) were significant for depression. However, only the age group 31-40 years was found to be more susceptible to anxiety. Conclusion: As important as addressing the psychological effects, knowing people at risk of developing mental illnesses will contribute effectively to providing appropriate psychological rehabilitation programs at the right time.

The psychological impact of COVID-19 and the subsequent social isolation on the general population of Karnataka, India