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A multitude of factors contribute to cancer disparities, including, but not limitedto, differences in diet, lifestyle, environmental exposures, cultural beliefs, geneticand biological factors related to ancestry, socioeconomic status (SES), andaccess to health care. More investigation is needed in evaluating these factors inless common cancers and hematological malignancies. Addressing disparities incancer incidence, prevalence, burden of disease, mortality, and survivorship thathave been documented among racial/ethnic minority populations with bloodcancers will require multilevel models of the interactions between relevant factorsand performance of translational research that uses knowledge of cancerbiology to develop and test the feasibility of interventions that can impact humanend points. Such work must address a wide range of research areas, includingprevention, early detection, diagnosis, treatment, epidemiology, cancer control,treatment, and survivorship. To be effective, efforts should be made to advancethese research findings to applications that can transform clinical practice and health care delivery. We reviewed the literature to define a framework for overcomingdisparities for patients with hematologic malignancies and to improve patient enrollment on clinical trials.

Strategies for Overcoming Disparities for Patients With Hematologic Malignancies and for Improving Enrollment on Clinical Trials