English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

To investigate the antidepressant Activity of the methanolic extract of the leaves of Musa x paradisiaca Linn This study was undertaken to evaluate the possible antidepressant effect of Musa x paradisiaca Linn leaf extract (MPLE) on different extracts like chloroform, methanol and aqueous extracts using Tail Suspension Test (TST) & Forced Swim Test (FST). 48 albino rats of either sex weighing between 180-220gm were randomly selected and divided into 8 equal groups. Group-I (control) received normal saline (1ml/100gm), GroupIV , V, VI, VII, VIII and IX received CEMPL (Chloroform Extract Musa x paradisiaca Linn) , MEMPL (Methanol Extract Musa x paradisiaca Linn) and AEMPL (Aqueous Extract Musa x paradisiaca Linn) in doses of 200 and 400 mg/kg orally (P.O.) respectively. Group II & III (positive control) received Fluoxetine & Imipramine at doses of 20mg/kg & 15mg/kg P. O. respectively. Drug treatment was given for seven & fourteen successive day. 60 minutes after last dose of drug or standard the immobility period was recorded. The test compounds like crude methanolic extract at 200, 400 and 500 mg/ kg produced significant antidepressant like effect. The efficacy of EALE at 200mg/kg was found to be comparable to that of Fluoxetine & Imipramine at doses of 20mg/kg & 15mg/kg.. The results revealed that the crude methanolic extract produces remarkable antidepressant activity by possessing the active compounds such as flavonoids, terpenes, alkaloids and saponins.

Evaluation of antidepressant Activity of methanolic Extract of Musa x paradisiaca Linn using animal models