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Agantu Vranas are shudha at initial stages but due to contamination at the time of accident, poor hygiene and lack of proper care by persons, these get vitiated by Tridosha frequently & convert into Dushta Vrana. The presence of Dushta Vrana worsens the condition of the patient and when associated with complications may become fatal. Objectives: To Study the Efficacy of Vidangadi Guggul in Dushta Vrana. To study the efficacy of Triphala Guggulu Orally in Dushta Vrana. Methodology: Randomized Controlled Clinical Trial, Total 67 patients of Dushta Vrana were enrolled in this study selected of age 18 to 60 year irrespective of sex, religion, occupation, economic and educational status. This study was approved by IEC of institute and written informed consent were taken before enrolment in the study. Trial group of 30 patients were given Vidangadi Guggulu 500 mg orally and Control group patients were given. Triphala Guggulu 500 mg orally were given for 30 days. Discussion: Dushta is one in which there is localization of three all the Doshas. Dushta Vrana, which had a bad odor, has abnormal color, irregular in size, with plentiful discharge, intense pain and takes a long period to heal. Dushta Vrana is a long-standing ulcer where removing debris enabling drug to reach healthy tissue is more important. In Ayurveda Dushta Vrana are treated effectively by Guggulu preparations like Triphala Guggulu and Vidangadi Guggulu. INTERNATIONAL AYURVEDIC MEDICAL JOURNAL Preeti G. Verma & Sandip Bhosale et al: Randomized Controlled Clinical Study To Evaluate The Efficacy Of Vidangadi Guggulu In Dushta Vrana doi:10.46607/iamj.2808102020 | IAMJ October 2020 | www.iamj.in 4754 Results & Conclusion: In trial group as well as control, there is significant difference observed on Day 0 and Day 30 in Size of Vrana, Vedana(pain) Srava (Discharge), Gandha (Smell), Edge of Vrana and Granulation tissue within group.

RANDOMIZED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF VIDANGADI GUGGULU IN DUSHTA VRANA