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Background and Objective: Ardhavabhedaka (migraine without aura) is characterized by severe tearing, pricking and piercing pain in one half of the head and giddiness which develops suddenly after ten days or a fortnight. Based on signs and symptoms it may correlate with migraine characterized by half sided headache associated with nausea, vomiting, photophobia and phonophobia. The current line of management for migraine advocates the use of analgesics and antiemetics, vasoconstrictors, sumatriptan, topiramate, flunarizine, Propranolol. Ayurveda emphasizes various treatment modalities of Ardhavabhedaka, includes both Shodhana and Shamana. Vidangadi avapeedana Nasya and Vidangadi arka (distillate) Nasya have been mentioned for ardhavabhedaka chikitsa. Arka is the essence of the drug; possesses laghu, ushna, kaphavatahara, increased potency, more shelf life, easy absorption and act fast. Materials and Methods: 20 patients of Group A were treated with Vidangadi Arka Nasya and Group B 20 patients were treated with Vidangadi Avapeedana Nasya (each nostril 6 drops for 7 days). Results: The data of both the groups were collected according to the objective and subjective Parameters and analyzed using repeated measures of ANOVA, Bonferroni test, and MannWhitney U Test. The efficacy was statistically highly significant within the group at P <0.001and statistically insignificant between the group at P >0.05 among all the parameters. Interpretation and Conclusion: Study can be concluded that patients treated with Vidangadi Arka and Avapeedana Nasya showed not much difference in the results statistically, clinically group A showed better results than group B. INTERNATIONAL AYURVEDIC MEDICAL JOURNAL Jeeva P et al: A Clinical Research On Open Labelled Clinical Control Study To Evaluate The Efficacy Of Vidangadi Arka Nasya In The Manage-ment Of Ardhavabhedaka (Migraine Without Aura) doi:10.46607/iamj.2608102020 | IAMJ October 2020 | www.iamj.in 4743

AN OPEN LABELLED CLINICAL CONTROL STUDY TO EVALUATE THE EFFICA-CY OF VIDANGADI ARKA NASYA IN THE MANAGEMENT OF ARDHAVABHEDA-KA (MIGRAINE WITHOUT AURA)