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ABSTRAK  Telah dilakukan penelitian   tentang   Penggunaan   Emulgator  VCO   ( Virgin Coconut Oil ) dalam sediaan krim transdermal asetosal. Penelitian ini bertujuan untuk: mengetahui apakah VCO (Virgin Coconut Oil) dapat diformulasikan ke dalam bentuk sediaan krim transdermal asetosal, untuk mengetahui konsntrasi VCO sebagai emulgator yang dapat menghasilkan sediaan krim transdermal asetosal yang memenuhi evaluasi sediaan yang baik. VCO diformulasikan  dalam bentuk sediaan krim transdermal asetosal dengan menggunakan tiga variasi konsentrasi. Penelitian ini merupakan penelitian eksperimental. Formulasi dilakukan dengan melihat parameter sifat fisik krim yang meliputi viskositas, daya sebar, daya lekat, pH, homogenitas, organoleptis, iritasi, cycling test setelah pembuatan. Hasil penelitian ini menunjukan bahwa VCO dapat diformulasikan ke dalam bentuk sediaan krim tra nsdermal asetosal, selain itu juga VCO dengan konsentrasi 16%, 18% dan 20% dapat digunakan sebagai emulgator dalam sediaan krim transdermal yang memenuhi evaluasi sediaan yang baik. Kata kunci :Virgin Coconut Oil, Asetosal, Transdermal, Krim, Emulgator   ABSTRACK  Research on the use of VCO (Virgin Coconut Oil) Emulgators in preparations of transdermal acetosal cream has been conducted. This study aims to: find out whether VCO (Virgin Coconut Oil) can be formulated into a transdermal acetosal cream dosage form, to find out the concentration of VCO as an emulgator that can produce transdermal acetosal cream preparations that meet a good dosage evaluation VCO is formulated in the form of acetosal transdermal cream preparations using three variations of concentration. This research is experimental research. This research is experimental research. The formulation is carried out by looking at the parameters of the physical properties of the cream which include viscosity, dispersion, adhesion, pH, homogeneity, organoleptic, irritation, cycling test after manufacture. The results of this study indicate that VCO can be formulated in the form of acetosal transdermal cream preparations, besides that VCO with concentrations of 16%, 18%, and 20% can be used as emulsifiers in transdermal cream preparations that meet good dosage evaluations Keywords; Virgin Coconut Oil, Acetosal, Transdermal, Cream, Emulgator

Penggunaan Emulgator VCO (Virgin Coconut Oil) Dalam Sediaan Krim transdermal Asetosal