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Objective: To evaluate the clinical pregnancy rates in intrauterine insemination (IUI) cycles performed with microfluidic sperm sorting chips. Material and methods: 133 patients who admitted to our tertiary infertility clinic and underwent ovarian stimulation and IUI protocol with microfluidic sperm sorting chip were analyzed respectively in terms of clinical pregnancy rates between January 2016-January 2020. Patients diagnosed with unexplained infertility, mild-moderate male factor, ovulatory dysfunction and mild endometriosis were included. Microfluidic sperm sorting chip was used for sperm preparation. Primary outcome was clinical pregnancy rates and secondary outcomes were the distribution of the rates according to a a . Results: Mean female age was 29.86 4.7 years, the mean total motile sperm count was 72.90 63.7 million, mean antral follicle count was 18.1 10.1, the mean total gonadotropin dose used was 897.6 366 IU. The causes of infertility were 54.1% unexplained infertility, 31.6% ovulatory dysfunction, 6% mild endometriosis, 8.3% mild male factor. The clinical pregnancy rate was 19.5% (26/133) as primary outcome. Infertile pa a 25 years have higher pregnancy rates as secondary outcome (25.9%). Conclusion: Microfluidic sperm sorting chips allow for a practical and rapid sperm preparation with acceptable clinical pregnancy rates. This method is more successful in younger infertile patients.

Experience of our clinic in intrauterine insemination cycles made with microfluidic sperm sorting chips