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The "self rating of the effects of alcohol" (SRE) questionnaire helps to identify persons with a low level of response to alcohol who might be prone to develop further alcohol-related problems. The questionnaire is a self-report of the number of drinks required to feel various states of inebriation in different periods of life: the first five times the subject ever drank alcohol, the time of heaviest drinking and alcohol use during three months preceding the interview. Each question aims to evaluate as precisely as possible the number of drinks taken to feel a specific effect. It does neither differentiate between innate sensitivity nor acquired tolerance. The SRE has been used in research with adult male populations and with middle-aged women. Adolescence is the period of initiation to alcohol use and provides a good opportunity for early prevention. In this sense the SRE might be useful for identifying at-risk subjects. Our study had two objectives. The first one was to assess whether an estimate of the level of response to alcohol could be related to drinking frequency and alcohol-related consequences. The second objective was to assess the characteristics (specificity and sensitivity) of the SRE-5 to identify binge-drinking adolescents and those with alcohol-related consequences. Level of response to alcohol was estimated in a sample of 68 boys and girls aged 15 to 21 over the first 5 experiences with alcohol (SRE-5).Adolescents participating in this research met the criteria of illicit drug or alcohol use (at least one substance once a week during the previous three months) at the beginning of the study. Adolescents with high SRE-5 scores reported heavier patterns of recent alcohol use and more alcohol-related adverse consequences. A cut-off of 4 on the SRE-5 was the most appropriate for identifying heavy drinkers but rates of sensitivity and specificity were rather low (78.6 and 63.8%). In conclusion, low level of response to alcohol estimated by elevated SRE-5 is associated with reported heavy drinking and alcohol problems for regular substance user adolescents but the SRE cannot be considered as an appropriate screening tool for clinical use with our sample. Our results provided a suitable context for developing appropriate instruments and prevention strategies pertinent to early alcohol use in adolescents. Some additional limitations should also be acknowledged. Results cannot be representative of the general population since the subjects were recruited in a select way (criteria for illicit drug or alcohol use, at least one substance once a week during the previous three months) and the sample size was relatively small. A larger sample would also allow for a better study of gender and age differences in regard to level of response to alcohol.

Identification of adolescents with a low level of response to alcohol using the «self rating of the effects of alcohol» questionnaire