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This study was conducted to investigate the responsiveness and its related factors of public health center for novel influenza A (H1N1) epidemic. The data was collected through a web-based survey conducted during February to April 2011. The 182 respon-dents were team leaders or persons who were responsible for H1N1-related work at public health centers during the H1N1 preva-lence. The related factors affecting the responsiveness were different by urban or rural area. In the level of gu (urban) area, coopera-tion with the public organizations, preparing its own response plan were the significant factors. But, in the level of si or gun (rural) area, cooperation with private organizations (clinic or pharmacy), physical (facilities, equipments, and medicines), and human infra-structures (public health professions, education and knowledge, and motivation) were more important factors. Therefore, how to cope with H1N1 prevalence in the future should be different by local characteristics. As a result, there are several challenges that public health centers should prepare for the further emerging infectious diseases. First, it is needed to make standard manuals which could strengthen education and training in order to respond appropriately, as well as to prepare enough physical infrastruc-tures for the crisis. Next, the public health center should prepare correct media response and cooperation system with public and private organizations.Keywords: H1N1 influenza; Public health center; Responsiveness

Responsiveness of Public Health Center and Its Related Factors against H1N1 Epidemic