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Ankylosing Spondylitis with Complete Atrioventricular Block and Aortic Regurgitation Shinya Fukui, Masataka Mitsuno, Mitsuhiro Yamamura, Hiroe Tanaka, Masaaki Ryomoto, Tetsuya Kajiyama, Ayaka Satoh and Yuji Miyamoto(Department of Cardiovascular Surgery, Hyogo College of Medicine, Nishinomiya, Japan) Ankylosing spondylitis is chronic, progressive, inflammatory disease involving the spine, peripheral joints, and periarticular structures. Cardiac abnormalities associated with ankylosing spondylitis are well recognized, but a case with DDD pacemaker implantation for complete atrioventricular block and aortic valve replacement for aortic regurgitation has not been previously reported. We report a case of a 66year-old man with ankylosing spondylitis who was successfully treated by DDD pacemaker implantation for complete atrioventricular block and aortic valve replacement for severe aortic regurgitation. Jpn. J. Cardiovasc. Surg. 44 : 241-244(2015)