Open AccessERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats
Author(s) -
Gustavo Alfredo Ochs de Muñoz,
Nélson Alexandre Kretzmann Filho,
Mónica Luján López,
Carlos Oscar Kieling,
Carolina Uribe Cruz,
Luciano Basso da Silva,
Alessandro Bersch Osvaldt,
Úrsula da Silveira Matte
Publication year - 2016
Publication title -
clinical and biomedical research
Language(s) - English
Resource type - Journals
ISSN - 2357-9730
DOI - 10.4322/2357-9730.68336
Subject(s) - mapk/erk pathway , bone marrow , medicine , hepatectomy , cancer research , immunology , microbiology and biotechnology , phosphorylation , biology , surgery , resection
We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation. Keywords: MAP Kinase Signaling System; stem cells; acute liver failure
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