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Amyotrophic Lateral Sclerosis (ALS) is a degenerative and fatal disease that changes the\udindividuals’ functionality. Physical therapy plays an important role in ALS by using assessment tools to evaluate\udfunctional performance. Objective: To investigate functional changes caused by ALS through 14 months in individuals\udwith and without physical therapy. Method: A cohort study conducted between 2010 and 2013 in the city of Natal-RN.\udThe study included patients in various stages of ALS, with no associated pathologies and those who were being\udmonitored by the Reference Center since 2010. Functional characteristics were categorized by applying the motor\uditems of Functional Independence Measure (FIM), Fatigue Severity Scale (FSS) and ALS-Functional Rating Scale\ud(ALSFRS). Participants were divided into two groups, those who performed physical therapy (FA) and those who\uddidn’t (CG). They were longwise evaluated in 3 different moments (1st day of assessment, four months after the first\udassessment and 10 months after the second evaluation). Nonparametric Friedman test was performed, considering\udp <0.05. Results: It was observed a significant functional decline in the control group (p <0.05) measured by the  ALSFRS. The CG also presented functional decline greater than the AF group from FIM scores, however without\udstatistical significance. There was no difference in the scores of FSS. Conclusion: Physical therapy can be a great\udadjunct in functional decline retardation in patients with ALS. It also emphasizes the importance of specific scales\udfor ALS, considering the disease progressive and heterogeneous nature

Perfil funcional de pacientes com Esclerose Lateral Amiotrófica ao longo de 14 meses de tratamento fisioterapêutico