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The administration of intrathecal opioids is a common technique when treating patients with chronic pain. The chosen drug is morphine due to its pharmacokinetic characteristics that determine a good analgesic quality, still required monitoring of patients for the first 24 hours because of their fundamental risk of respiratory depression. We present a case of hearing loss associated with opioid intoxication after administration of morphine by intrathecal infusion pump in a patient with chronic pain with post-laminectomy syndrome. The patient was treated with respiratory support and continuous intravenous infusion of naloxone. The hearing loss reverted within one hour after gradual increase of the treatment. The different articles that we analyzed include nausea, vomiting, pruritus, urinary retention and respiratory depression as side effects of intrathecal morphine. There is no reference to the onset of hearing loss associated with intrathecal opioid intoxicaton in the literature we have reviewed so far.

Hipoacusia en un paciente tras administración de morfina intratecal