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Anisakis simplex can be a cause of digestive symptoms. Our aim was to evaluate the epidemiological an tecedents and immunological data available for a differentiation betweenpatientswithanisakidosisandthosewithotheracuteab dominalproblems. Patients and methods: thisisaprospectivecohortstudyin volving 134 patients with acute abdominal problems: 52 patients werediagnosedwithanisakidosisbymeansofsurgicalandpatho logical findings and/or specific IgE seroconversion against Anisakis simplex (group A), and in 82 patients anisakidosis had been ruled out (group NA: non-anisakidosis). We evaluated the antecedent of raw fish ingestion, the skin prick test, and IgE im munoblottingasdiagnostictools. Results: patients in groups A and NA differ in terms of prior raw fish ingestion (p < 0.0001) and positive SPT (p < 0.0001), with their respective negative predictive values (NPV) being 98.39% (95%CI: 90.17-99.92) and 95.56% (95%CI: 83.64

Utilidad de la anamnesis y de las técnicas inmunológicas en el diagnóstico de la anisakidosis en pacientes con abdomen agudo