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The hepatitis A virus (HAV), a picornavirus, is a common cause of hepatitis worldwide. Hepatitis A remains an important cause of community-acquired hepatitis. Spread of infection is generally person to person or by oral intake after fecal contamination of skin or mucous membranes; less commonly, there is fecal contamination of food or water. Hepatitis A is endemic in developing countries, and most residents are exposed in childhood. In contrast, the adult population in developed countries demonstrate falling rates of exposure with improvements in hygiene and sanitation (1). Presently, many tropical countries are classifie as endemic area for viral hepatitis A. In Thailand, hepatitis A infection is still an important viral infectious disease. A recent study indicated that up to 97% of the Thai adults had natural immunity to this disease (2). There have been sporadic reports on the outbreak of this infection for years. Here, the authors performed a summarization on the previous reports on the outbreak of hepatitis A infection in a 25 years period, from 1980 to 2005. A literature review to find the reports on outbreak of hepatitis A in during that period in Thailand was performed. The author used the electronic search engine PubMed (www.pubmed.com) in searching for the literatures. The author also reviewed the published works in all 256 local Thai journals, which is not included in the international citation index by the database Thai Index Medicus. According to this study, there are at least 6 reports (3-8) on the outbreak of hepatitis A during 1980 to 2005 (Table I). There had been continuous reports on sporadic hepatitis A outbreak in Thailand during 1980’s and early 1990’s. However, there was no report after 1993. The numbers of reported cases in the outbreak range from 13 to 1,214 cases. The settings of outbreaks can be found in many settings, especially in schools (4/6 reports). The period of epidemic usually occurred in 1-2 months, with the common starting point in the rainy season of Thailand. The common sources of infections are water in 5 reports and food in 1 report. According to this study, there is a trend of decrease report of hepatitis A outbreak in the last decade. This finding might imply the improvement in health education and control of this hepatitis disease in Thailand. Concerning the reported outbreak in this study, there are both reports of the outbreak among the children and adults. In this study, water is the main source of infection. Untreated contaminated drinking water is common (3,4,6). It seems that treated running tap water is important in prevention of hepatitis outbreak (9). However, well treated drinking water but later contaminated due to sharing cup can be seen (7). Therefore, the self-sanitation in drinking is important. Similar to many reports, the school is a common place for the outbreak of hepatitis Letters to the editor 1130-0108/2008/100/2/109-116 REVISTA ESPAÑOLA DE ENFERMEDADES DIGESTIVAS Copyright © 2008 ARÁN EDICIONES, S. L. REV ESP ENFERM DIG (Madrid) Vol. 100, N.° 2, pp. 109-116, 2008

Hepatitis A outbreak in Thailand during the past 25-year period, a summary.