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espanolLos PBDEs son sustancias potencialmente peligrosas liberadas del reciclaje de e-waste. La evidencia cientifica implica a los PBDEs en alteraciones en la salud como cancer, alteraciones endocrinas y problemas en la descendencia. Se han encontrado elevadas concentraciones en muestras biologicas (suero, pelo, leche materna y cordon umbilical) de los trabajadores expuestos, por lo que su exposicion implicaria un potencial riesgo para la salud para los trabajadores y su descendencia. Objetivo: Identificar la evidencia existente entre exposicion a PBDEs contenidos en e-waste y los danos sobre la salud en trabajadores de la industria del reciclaje. Material y metodos: Se realizo una revision sistematica de la literatura cientifica publicada entre 2003 y 2013, en siete bases de datos mediante terminos MeSH. Las referencias se cribaron en funcion de los objetivos. Resultados: Se recuperaron 301 articulos y se incluyeron en la revision 20. El 65% fueron realizados en China, el 80% respondian a un diseno transversal. Los estudios evidencian una asociacion entre exposicion a PBDEs y los niveles de PBDEs en distintas muestras biologicas. Los trabajadores presentaron mayores niveles de marcadores de dano al DNA. Los efectos de la exposicion a PBDEs sobre la funcion tiroidea no fueron consistentes. Conclusiones: La literatura revisada evidencia una asociacion entre exposicion a PBDEs y alteracion de parametros biologicos en trabajadores de la industria del reciclaje. No puede establecerse una relacion de causalidad por el tipo de diseno empleado. Los estudios de intervencion evidencian la eficacia de las medidas de mejora para disminuir la exposicion a PBDEs. EnglishPBDEs are potentially dangerous substances released during the e-waste recycling processes. Scientific evidence relates PBDEs with adverse health outcomes like cancer, endocrine disruptions and problems in the offspring. A high concentration of PBDEs has been found on biological samples (serum, hair, breast milk and umbilical cord) from exposed workers, so their exposure could imply a potential risk on workers' health. Aim: To summarize the evidence between exposure to PBDEs contained in e-waste and adverse health outcomes on recycling industry workers. Materials and methods: A systematic review was done among the scientific literature published between 2003 and 2013 in seven data bases using Medical Subject Headings (MeSH) terms. Results: 301 articles were evaluated and 20 were included in the review. 65% were from China, 80% had a cross-sectional design. We assessed evidence of association between exposure to e-waste and levels of PBDEs in several biological samples. Workers showed high levels in the DNA damage markers. The effects from the exposure to PBDEs on the thyroid function were not consistent. Conclusions: Findings from most studies shows a correlation between the exposure to PBDEs and the alteration of the biological parameters on the recycling industry workers, but our ability to assess temporality associations was limited by the small number of prospective and longitudinal studies. Conventional industrial hygiene improvements in e-waste recycling facilities may reduce the exposure on workers to PBDEs.

Efectos biológicos derivados de la exposición a PBDES en trabajadores del reciclaje de e-waste: revisión sistemática