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espanolLa prevencion del cancer de cuello uterino ha evolucionado rapidamente a consecuencia de la identificacion de su causa, el Virus del Papiloma Humano (VPH). La asociacion VPH/Cancer de Cuello Uterino, es aplicable tanto al carcinoma escamocelular como al adenocarcinoma. Dos de los tipos oncogenicos, los VPHs 16 y 18, son responsables del 70% de los casos de cancer de cuello uterino a nivel mundial. El VPH es muy prevalente entre personas sexualmente activas, y se puede identificar facilmente mediante el uso de tecnologias capaces de detectar ADN y otros biomarcadores del VPH. El ADN y los biomarcadores se pueden detectar en todas las fases de la historia natural de la infeccion y del proceso neoplasico. Dicha trazabilidad unida a la validacion clinica de las tecnologias de identificacion, han permitido mejorar los protocolos de cribado del cancer cervical. La proteina principal del virion, ya expresada, produce inmunogenos capaces de inducir fuertes respuestas inmunitarias cuando se administran via intramuscular, y esta es la base de la Vacuna frente a VPH. EnglishThe UCC (Uterine Cervical Cancer) prevention has suffered a great evolution because of the knowing of its cause, wich is the HPV (Human Papillomavirus). The association HPV / UCC is available also to Scamocellular Carcinome to Adenocarcinome. Mundially, the oncogenic types, 16 and 18, are responssible of 70% of cases of UCC. HPV is very prevalent in sexually active people, and it’s easy identify by using DNA amplyfiyng technologies and other biomarkers. These ones can be detected in hole virus natural life, including the neoplasic process. The tazability and the clinic validation of this technologies, have improved to get a better screening of the UCC. The main HPV protein, is able to produce a strong inmunitary response, when it’s given by intramuscular punctury; and this is the explanation of the HPC vaccine.

Las 47 preguntas sobre el virus del papiloma humano, VPH