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This is a prospective comparative randomized study carried out at Kosti teaching hospital 2006-2008. Objectives : to determine the radiological findings and to evaluate the radiological progress in patient with pulmonary Tuberculosis treated with daily versus intermittent short course regimens. Methodology : A total of 275 smear positive new cases of Tuberculosis were enrolled and randomized in to two groups, intermittent group (A) and daily regimen group (B) .X-Ray film was done initially and at the end of treatment for each patient. Results : It was found that 31% of the X-Ray films were normal.  Concerning the progress of minimal lesion significantly high percentage improved to normal X-Ray 58% in group A and 53 % in group B , 42 % in group A and 40 % in group B stayed as minimal lesion. The results of far advanced lesion revealed that intermittent regimen improved 16.6% of the films to normal and minimal lesion , 8.3 % to moderate lesion, 33.3 % moderately advanced lesion and 25 % remained unchanged, while in the daily regimen , 21 % improved to normal and minimal lesion , 5.2 % to moderate lesion , 27 % to moderately advanced lesion and 27.6 %. Statistical analysis revealed a significant difference between the two groups. Conclusion : Conversion of minimal lesions to normal X-Ray was  significantly higher in the intermittent group and the conversion of far advanced lesions to normal was significantly higher in the daily regimen.

Radiological changes and progress in patient with pulmonary Tuberculosis following treatment with daily versus intermittent short course regimens