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The effects of various doses of dietary intake of Garcinia kola seed powder [incorporated in animal feed at levels of 5% w/w, 10% w/w and 20% w/w and fed daily for six weeks] on serum levels of selected electrolytes [K+, Na+, CI-, HCO3-, Mg2+ and Ca2+] and trace metals [Cu2+, Zn2+ and Mn2+] were studied in male Albino rats [100-150 g body wt]. The pair-fed controls received basal feed diet daily for six weeks. Results showed a significant [P&lt;0.05] dose dependent elevation of serum CI-, HCO3-, Ca2+, Mg2+, Cu2+, Zn2+ and Mn2+. These findings point to a possible relationship with already documented histopathology of various organs [such as the gonads] induced by Garcinia kola seed. It is also conjectured that the documented antibacterial, anti-inflammatory, anti-spasmodic, antidiabetic and antifertility effects of Garcinia kola seed may have underlying involvement of alterations in body levels of trace metals and electrolytes.

Effect Of Dietary Garcinia Kola Seed On Selected Serum Electrolytes And Trace Metals In Male Albino Rats