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Chronic suppurative otitis media (CSOM) is a challenging disease with a high burden on society in developing countries. Information regarding CSOM in Sudanese patients is scarce. This study aimed to identify aerobic bacteria involved in CSOM and to determine their sensitivity towards commonly prescribed antibiotics. A multi-center prospective cross sectional study was conducted between June 2012 and October 2013 in private and public ENT clinics in Gezira State, Sudan. The study included 217 CSOM patients most of whom were males or had unilateral disease. The most common isolates were Staphylococcus aureus (42.6%), Klebsiella pneumoniae (14.7%), Pseudomonas aeroginosa (12.5%) and Proteus mirabilis (10.2%). The sensitivity of all isolates was highest towards gentamicin and ciprofloxacin while multiple drug resistance was prominent towards amoxyclav, cotrimoxazole, cefuroxime, cefaclor and ceftriaxone. Ciprofloxacin and gentamicin appear to be the best choices for empiric therapy in patients with CSOM. In contrast, the use of amoxyclav, cotrimoxazole, cefuroxime, cefaclor and ceftriaxone should be discouraged . Keywords : Aerobic bacteria, Chronic suppurative otitis media, Gezira State, Sudan

Aerobic bacteria in safe type chronic suppurative otitis media in Gezira State, Sudan