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Objectif : L’objectif de la presente etude a ete de rechercher les effets de l’Amprolin-300, un anticoccidien largement utilise en medecine veterinaire, sur quelques parametres de croissance et de reproduction chez le lapin mâle de race locale. Methodologie et resultats : Vingt-quatre (24) lapins âges de 5 mois environ et pesant entre 2,01 et 2,78 kg ont ete repartis en 4 lots comparables de 6 lapins chacun. Ils ont ete traites pendant 60 jours avec differentes doses d’Amprolin-300 ws via l’eau de boisson : 0 ; 30 ; 60 et 110 mg/kg de poids corporel. Les resultats obtenus ont revele que la consommation d’eau a significativement (p<0,05) diminue chez les lapins traites aux doses 60 et 110 mg/kg de poids corporel par rapport aux temoins. Le gain de poids et le gain moyen quotidien ont diminue de maniere significative (p<0,05) chez les animaux traites aux doses 30 et 60 mg/kg de poids corporel par rapport aux animaux du lot temoin. Par contre, l’indice de consommation a diminue de facon significative (p<0,05) chez les animaux temoins et chez ceux qui ont ingere la plus forte dose d’Amprolin-300 ws (110 mg/kg de poids corporel) compare aux lapins traites avec les doses 30 et 60 mg/kg respectivement. Le pH de la semence a significativement (p<0,05) augmente chez les mâles traites aux doses 30 et 60 mg/kg de poids corporel par rapport Aux mâles du lot temoin. La motilite individuelle et la concentration des spermatozoides ont diminue de maniere significative (p<0,05) chez les lapins qui ont ingere la plus forte dose d’anticoccidien par rapport aux lapins temoins. Conclusion et application des resultats : Ainsi, a la dose de 110 mg/kg de poids corporel, l’Amprolin-300 ws a reduit la consommation alimentaire, le gain de poids, le gain moyen quotidien, le poids specifique et le pH de la semence. Cette dose a egalement inhibe la spermatogenese et reduit le pourcentage de spermatozoides mobiles. Son usage devrait donc etre reglemente. Mots cles : Amprolin-300 ws, lapin mâle, production et fertilite. Objective : In this study, the effects of Amprolin-300 ws, an anticoccidiostat abundantly used in veterinary medicine, on some growth and reproductive parameters in male rabbits were investigated. Methodology and results : Twenty four (24) rabbits aged 5 months and weighing between 2.01 and 2.78 kg were divided into 4 comparable groups of six rabbits each and treated for 60 days with different doses of Amprolin-300 ws from drinking water: 0, 30, 60 and 110 g/kg of body weight. The results showed that water consumption was significantly (p<0.05) decreased in rabbits treated with 60 and 110 mg/kg of body weight of Amprolin-300 compared to control rabbits. Body weight gain and average daily gain decreased significantly (p<0.05) in animals treated with 30 and 60 mg/kg of body weight compared to control rabbits. On the other hand, feed efficiency decreased significantly (p<0.05) in control animals and those who ingested the highest dose (110 mg/kg of body weight) compared to rabbits treated with 30 and 60 mg/kg of body weight respectively. The pH of semen increased significantly (p<0.05) in animals treated with 30 and 60 mg/kg of body weight compared to control animals. Individual motility and sperm concentration decreased significantly (p<0.05) in rabbits who received the highest dose of Amprolin-300 compared to control rabbits. Conclusion and application of results : Thus, at the dose of 110 mg/kg body weight, Amprolinws-300 reduced in male rabbit, food consumption, body and average daily weight gain, specific weight and pH of semen. It inhibited spermatogenesis and reduced sperm mobility. Therefore its use should be regulated.

Effets de l’amprolin-300 Ws sur quelques paramètres de croissance et de reproduction chez le lapin mâle (<i>Oryctolagus cuniculus</i>)