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Les plantes aromatiques jouent un role considerable dans plusieurs secteurs notamment dans la medicine traditionnelle. Dans le but de la valorisation de ces plantes, ce travail a pour objectif d’evaluer la relation composition chimique-activite antioxydante, et la toxicite des huiles essentielles de Cymbopogon citratus et Cymbopogon schoenantus acclimatees au Benin. Les huiles essentielles (HE) ont ete obtenues et analysees par CPG/DIF et CPG/SM. Le test antioxydant a ete realise par la methode de DPPH et celui de la toxicite sur les larves de crevette de Artemia salina Leach. L’analyse chimique a revele plusieurs composes dont le citral a 75% dans l’HE de Cymbopogon citratus et la piperitone a 60,3% dans celle de Cymbopogon schoenantus . L’activite antioxydante varie d’une plante a une autre avec l’huile de Cymbopogon schoenantus (CE 50 = 5040 μg/mL) plus antioxydante que celle de Cymbopogon citratus (CE 50 = 47860 μg/mL). Cette activite de l’huile de Cymbopogon schoenantus pourrait s’expliquer par la presence de constituants comme la piperitone et le limonene, reconnus pour leurs proprietes antioxydantes. Toutes les huiles etudiees sont moins antioxydantes que le compose de reference (acide ascorbique; CE 50 = 20 μg/mL), et moins toxiques (CL 50 ˃30 μg/mL) que la camptothecine (CL 50 = 13,27 μg/mL). Ces huiles essentielles, moins toxiques et deja utilisees dans la medicine traditionnelle, pourraient egalement contribuer a la prise en charge des maladies dues aux radicaux libres. © 2019 International Formulae Group. All rights reserved Mots cles: Plantes aromatiques, composes volatils, Artemia salina Leach, antioxydants, medecine traditionnelle English Title:  Relationship between chemical composition, antioxidant activity and toxicity of essential oils from two species of Cymbopogon acclimated in Benin English Abstract Aromatic plants play a considerable role in several sectors, especially in traditional medicine. In order to promote these plants, this work aims at evaluating the relationship between chemical composition, antioxidant activity and the toxicity of the essential oils of Cymbopogon citratus and Cymbopogon schoenantus acclimated  in Benin. Essential oils (EO) were obtained and analyzed by GC/FID and GC/MS. The antioxidant test was carried out by the DPPH method and the toxicity test against shrimp larvae of Artemia salina Leach. Chemical analysis revealed several compounds including 75% of citral in Cymbopogon citratus EO and 60.3% of piperitone in Cymbopogon schoenantus one. The antioxidant activity varies according to the species with the oil of Cymbopogon schoenantus (EC 50 = 5040 μg/mL) more antioxidant than that of Cymbopogon citratus (EC 50 = 47860 μg/mL). This activity of the Cymbopogon schoenantus oil could be explained by the presence of constituents such as piperitone and limonene, known to possess antioxidant properties. All the studied oils are less antioxidant than the reference compound (ascorbic acid, EC 50 = 20 μg/mL), and less toxic (LC 50 ˃30 μg/mL) than camptothecin (LC 50 = 13.27 μg/mL). These essential oils, less toxic and already used in traditional medicine, could also contribute to the management of diseases caused by free radicals. © 2019 International Formulae Group. All rights reserved Keywords: Aromatic plants, volatile compounds, Artemia salina Leach, antioxidants, traditional medicine

international journal of biological and chemical sciences

Relations entre composition chimique, activité antioxydante et toxicité des huiles essentielles de deux espèces de &lt;i&gt;Cymbopogon&lt;/i&gt; acclimatées au Bénin