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A cross-sectional study involving a questionnaire, parasitological examination of cattle and entomological prospection were conducted in the Mezam Division of Cameroon from December 2013 to May 2014 in two seasons for the first time. The objectives were to determine the prevalence of bovine trypanosomiais and its vectors. Peasant farmers n=95 were interviewed. Standard protocols for parasitological, hematocrit analysis as well as trypanosome identification were used. Acetone baited blue biconical traps n=5 were used for entomological survey. Questionnaire survey revealed that trypanosomiasis was one of the major health problems affecting animals and a hindrance to agricultural activities. The overall prevalence was 10.3% 31/301. Trypanosome species identified consisted of: T. vivax (58.1%), T. brucei  (25.8%), T. congolense (9.6%) and a mix infection ( Trypanosoma congolense + Trypanosoma vivax ) (6.5%). Vector survey revealed highest fly catch in Bafut subdivision as compared to others with a significant difference P<0.05. Fly types recorded included: Tabanus 125 (71.4%), Stomoxys 31 (17.7%) and Glossina morsitans submorsitans 19 (10.9%). The overall Apparent Density (AD) was 1.53 fly per trap per day (f/t/d). Therefore, vector transmission and impact of the disease on production is alarming and should not be neglected. Control strategies have to be designed and implemented in Mezam Division in order to eradicate trypanosomiasis and its vectors. © 2016 International Formulae Group. All rights reserved. Keywords: Cattle, trypanosomiasis, Glossina , prevalence, Bafut

Preliminary assessment of bovine trypanosomiasis and its vectors in Santa, Bali and Bafut Sub-Divisions of the, North West Region, Cameroon