English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The study was set up to review the current susceptibility patterns of Salmonella isolates to quinolones. A systematic literature search on in vitro and in vivo susceptibility patterns of Salmonella isolates to various quinolones was carried out from relevant published articles over a 25 year interval (1982-2007). Data obtained was analysed using simple descriptive methods. Susceptibility patterns of 55,853 Salmonella isolates to quinolones from 845 reports were reviewed. The most active quinolones encountered were (where n= number of Salmonella isolates tested): ciprofloxacin, 99%(n=15,432); grepafloxacin, 99%(n=2,701); gemifloxacin, 97%(n=1,209); ofloxacin, 96%(n=8,692); and sparofloxacin, 93%(n=557). This was followed by: enoxacin, 92%(n=2,653); gatifloxacin, 90%(n=788); lomefloxacin, 83%(n=1,823); and levofloxacin, 81%(n=3,228). And the least active quinolones against Salmonella spp. were norfloxacin, 76%(n=1,355); pefloxacin, 62%(n=4,307); and nalidixic acid, 61%(n=17,542). Quinolones at present have been found to be quite effective in the management of enteric fever and their use should be sustained. However, susceptibility patterns of the local Salmonella isolates should be conducted to identify the most appropriate quinolone to use in this environment. Furthermore, in the absence of a susceptibility report, ciprofloxacin, grepafloxacin, gemifloxacin, ofloxacin, and sparofloxacin may be considered preferred choices on proven diagnosis of enteric fever.

Quinolones and their clinical relevance in the management of enteric fevers in the new millennium: Findings from a review of 55,853 &lt;i&gt; Salmonella&lt;/i&gt; isolates