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A cross - sectional survey was conducted from 17 Oct. to 11 Dec. 2008 with the aim of determining the sero-prevalence and the major risk factors of contagious caprine pleuropneumonia (CCPP) in the selected eight districts of Afar region namely: Afambo, Assaita, Dubti, Mille, Gewane, Amibara, Dewe and Telalak. During the study a total of 329 goat sera, was examined for the presence of specific antibodies against Mycoplasma capricolum sub. spp. capripneumoniae using CFT. The result revealed that 22.49% (74) prevalence rate. With respect to goats origin, the serological prevalence rates was 31.85%, 36.36%, 18.75%, 12.50%, 12.16%, 10%, 22.22%, and 19.56% from Afambo, Assaita, Dubti, Mille, Gewane, Amibara, Dewe and Telalak districts respectively. The result indicated that there is significant difference (P Keywords: Afar region, CCPP, Goat, Sero-Prevalence, Risk factors, CFT

Sero-Prevalence of Contagious Caprine Pleuropneumonia in Goat at Selected Woredas of Afar Region