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Dans le cadre de la valorisation de la pharmacopee africaine en general et camerounaise en particulier, des decoctions de feuilles de Ricinus communis, Harungana madagascariensis, Erigeron floribundus, Chromoleana odorata et Lantana camara ont ete etudiees in vitro pour leur activite antibacterienne. Trois souches bacteriennes dont Staphylococcus aureus, Escherichia coli et Bacillus subtilis souvent responsables de processus morbides ont ete utilisees. Les tests ont ete realises in vitro suivant la technique standard de macro dilution en tube et en milieu liquide. Les concentrations qui evoluaient en progression geometrique de raison deux ont permis de constater que les cinq preparations presentent une inhibition de la croissance bacterienne. Les concentrations minimales inhibitrices (CMI) variaient entre 0,05x10 -2 et 2,94x10 -2 gramme de Matiere Seche par millilitre (g de MS/ml) de decoction. Toutes les preparations ont une bactericidie variable entre 0,4x 10-2 et 12,61.10 -2 g de MS/ml de decoction. Les cinq decoctions presentent une action bactericide sur  S. aureus comprise entre 0,40x10-2 et 11,75x10 -2 g de MS/ml. Par contre, une absence de bactericidie est observee avec R. communis et H. madagascariensis sur  E. coli et chez H. madagascariensis, E. floribundus et L. camara sur B. subtilis . Cette etude revele une difference de sensibilite des bacteries aux decoctions etudiees. L’action bactericide des cinq extraits est identique pour S. aureus avec un coefficient phenol de 30. La meilleure efficacite est obtenue avec E. floribundus sur E. coli et R. communis sur B. subtilis qui presente le coefficient phenol le plus eleve. In vitro evaluation of antimicrobial activity of some Adamawa (Cameroon) medicinal plants. In the bid to develop pharmacology in Africa and Cameroon in particular, the leaf extracts of five: Ricinus communis, Harungana madagascariensis, Erigeron floribundus Chromoleana odorata and Lantana camara were tested in vitro for  their  antibacterial  activities on three common pathogenic bacterial species namely Staphylococcus aureus , Escherichia coli and Bacillus subtilis . The in vitro tests were carried out using a tube macro-dilution technique. Two–fold geometric concentrations of the various extracts were tested against the bacterial species. Results obtained showed varied bacteriological efficacy of the extracts tested, with minimum inhibitory concentrations (MICs) ranging between 0.05 x 10 -2   and 2.94 x 10 -2   g of the dry extract/ ml. The various extracts tested demonstrated good in vitro efficacy against S. aureus with concentrations varying from 0.4 x10 -2 to 11.75 x10 -2 g of dry extract/ml. However, a much limited spectrum of activity was observed for the other bacterial species. R. communis and H. madagascariensis had no in vitro activities on E. coli, while H. madagascariensis and E. floribundus were not effective against B. subtilis. The same phenol coefficient of 30 indicated similar antibacterial effect on S. aureus.  Regarding the phenol coefficient, the best effect was obtained with E. floribundus on E. coli and R. communis on B. subtilis .

Evaluation in vitro de l’activité antibactérienne de cinq plantes de la pharmacopée traditionnelle de l’Adamaoua (Cameroun)