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Background: Intestinal coccidia are group of protozoa which parasitize the epithelial cells of the intestinal tract of their hosts. Most infections usually produce mild, self-limiting infections in man, but they now constitute a serious public health problem, especially in developing countries with inadequate sanitary conditions coupled with widespread HIV/AIDS infection. Objective: To determine the Prevalence of intestinal coccidian parasites burden in HIV/AIDS patients on antiretroviral therapy in HIV Centers in Mubi, Nigeria Materials and Methods: This was a hospital-based cross-sectional study in which stool specimens from  IV-positive patients on ART were examined for the presence ofoocysts of intestinal coccidian parasitesusing Modified Acid Fast Stain technique. In addition, patients’ blood samples were analyzed for CD4 count by flow cytometry and packed cell volume (PCV) through microhaematocrit centrifugation. Results A total of 305 specimens examined, 236(77.4%) were positive for Cryptosporidium parvum, Isospora belli and Microsporidium species. Patients within the age group of 21 – 30 were the most infected. Generally, the  duration of ART influenced the prevalence of the intestinal coccidian parasites. There was a highly significant  association between the CD4 count and prevalence coccidian parasites (p ˂ 0.05). There was a significant  negative correlation (r = -0.95) between the duration of the ART and the prevalence of coccidian presence. Conclusion: Routine screening of HIV-positive patients for intestinal parasites is advocated as standard operative procedure (SOP) before antiretroviral therapy (ART) is given. Construction of public health facilities, toilets and boreholes as well as public enlightenment campaign is recommended for more effective management of these patients. Keywords: intestinal coccidian parasites, antiretroviral therapy, Mubi Contexte: Les coccidies intestinales sont un groupe de protozoaires qui parasitent les cellules epitheliales du tube digestif de leurs hotes. La plupart des infections humaines sont d'habitude peu severes et autolimitees, mais elles constituent de nos jours un veritable probleme de sante publique, particulierement dans des pays en voie de developpement ou les conditions sanitaires sont inadequates, et couplees a l'infection repanduedu VIH/SIDA. Objectif: Determiner la frequence de coccidies intestinales chezles patients atteints de VIH/SIDA sous traitement antiretroviral dans les Centres de controle de VIH de Mubi au Nigeria. Materielset Methodes: Il s’agissait d’une etude transversale dans laquelle les specimens de selles des patients seropositifs au VIH et sous traitement antiretroviraletaient examines en vue d’en depister la la presence  d’oocystes de coccidies intestinales grâce a la technique de de coloration acido-resistante modifiee. De plus, les  prelevements de sang des patients etaient analyses pour en determiner le taux de CD4 et le taux demicro-hematocrite par les techniques de flux cytometrique et de centrifugation respectivement. Resultats: Untotal de 305 specimens ont ete examines, 236 (77.4 %) etaient positifs pour le Cryptosporidiumparvum ,le Isospora belli et les especes de Microsporidie. Les patients dans la tranche d'âge de 21 – 30 ans etaient les plus infectes. Generalement, la duree du traitement antiretroviralinfluencait la frequence des coccidies intestinales. Il y avait une association fortement significative entre le taux de CD4 et les infections(p< 0.05). Il existait une correlation negative significative (r =-0.95) entre la duree detraitement antiretroviralet la frequence de coccidies intestinales. Conclusion: Le depistage de routine des patients seropositifs pour des parasites intestinaux est preconise dans la procedure operatoire standard avant toute administration de therapie antiretrovirale. La construction d'installations de sante publique, des toilettes et des puits de forage ainsi que des campagnes  d'educationsanitaire sontfortement recommandees en vue d’une prise en charge effectivedes patients atteints de VIH. Mots-cles : coccidies intestinales, therapie antiretrovirale, Mubi Article in English.

The Prevalence of Intestinal Coccidian Parasites Burden in HIV/AIDS Patients on Antiretroviral Therapy in HIV Centers in Mubi, Nigeria