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Peripheral blood lymphocytes were cultured in vitro in the presence of a mitogen; Concanavalin A (Con A), this resulted into a process described as lymphocyte transformation. The morphological changes in the cells were studied using phase contrast and electron microscopes. The results presented corroborated the existence of lymphocyte heterogeneity in tilapias.

Proliferative responses of tilapia T-like lymphocytes to stimulation by Concanavalin A