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Two edible Nigerian macro-fungi Lycoperdon pusilum and Lycoperdon giganteum were assayed in-vitro for their antimicrobial activities using water, methanol and ethanol as extractive solvents. Generally, the extracts were selectively active on few clinical pathogenic microorganisms. Ethanol was the best extractive solvent followed in order by methanol and water (P inhibitory concentration (MIC) for the ethanolic extract was between 0.75 and 4.0mg/ml for bacteria, and between 9.00 and 13.75mg/ml for fungi. The extracts were found to be stable at temperatures up to 50oC. As the temperature was increased from 60 to 100oC, there was a significant decrease in stability of the extract. The implications of these observations are discussed.

Antimicrobial activities of two Nigerian edible macro-fungi-lycoperdon pusilum(Bat. Ex)and lycoperdon giganteum(Pers.))