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Restless legs syndrome (RLS) is considered a genetic disease and, following a genome-wide association study conducted in 2007, the mitogen-activated protein kinase 5 (MAP2K5) gene has been regarded as the promising candidate gene for RLS. The present study investigated whether polymorphisms of MAP2K5 are associated with antipsychotics-induced RLS in schizophrenia.

psychiatry investigation

Haplotype Association of the &amp;lt;italic&amp;gt;MAP2K5&amp;lt;/italic&amp;gt; Gene with Antipsychotics-Induced Symptoms of Restless Legs Syndrome among Patients with Schizophrenia