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In recent years, there has been a dramatic increase in abuse of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV), often in combination with other illicit stimulants.

Sensitization to the Motor Stimulant Effects of 3,4-Methylenedioxypyrovalerone (MDPV) and Cross-Sensitization to Methamphetamine in Rats