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Leiomyomas are infrequent solid, benign lesions of the kidney which arises from smooth muscle cells of various structures of kidney such as renal capsule, pelvis or vascular smooth muscle (1). In spite of their rarity within the genitourinary system, leiomyomas are frequently detected in the kidneys and are less often non-epithelial benign tumors of the bladder (2). Kidney leiomyomas are often identified between the second and fifth decade of life, with a median age of 42 years and a female predominance. Although the majority of kidney leiomyomas in the literature are adults, they can also be detected in children. Symptoms of leiomyomas vary according to localization in the urinary system, whereas those originating from the kidney often do not cause symptoms and may radiologically mimic other malignant masses of the kidney (3,4).

Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma