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The major adverse effect of doxorubicin (DOX) in cancer treatment is cardiac toxicity. Murva is a controversial plant used in the Ayurvedic system, which consist of more than 12 medicinal plant roots found in different parts of India. Marsdenia tenacissima (MT) is an acceptable source in Murva, whereas Sansevieria roxburghiana (SR) Schult &amp; Schult.f. ( S. zeylanica Roxb.) are also considered as Murva in West Bengal, India. The present study focused on the evaluation of the cardioprotective mechanism as well as the in vivo cardioprotective potential of methanol extracts of MT and SR on rats by using in silico methods.

turkish journal of pharmaceutical sciences

Cardioprotective Effect of &lt;i&gt;Marsdenia tenacissima&lt;/i&gt; and &lt;i&gt;Sansevieria roxburghiana&lt;/i&gt; in Doxorubicininduced Cardiotoxicity in Rats &lt;i&gt;in vivo&lt;/i&gt;: The Role of Dresgenin and Lupeol