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In recent years, the design of anticholinesterase agents based on molecular hybridization of pharmacologically active scaffolds has attracted a great deal of interest in medicinal chemistry. For this purpose, we aimed to design and synthesize anticholinesterase agents based on the molecular hybridization of thiazole and pyrazoline scaffolds.

Synthesis and Evaluation of A New Series of Thiazolyl-Pyrazoline Derivatives as Cholinesterase Inhibitors