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It is well-known that β-thalassemia is associated with changes\udin plasma lipids and lipoproteins [1,2,3]. To our knowledge, no\uddata are available on lipid profiles in Turkish β-thalassemia\udmajor (TM) and β-thalassemia trait (TT) patients together. The\udaim of this study was to evaluate lipid profiles in two groups of\udpatients with β-TM and β-TT and to compare them with healthy\udcontrols. The study included a total of 311 subjects. Group 1\udincluded 131 β-TM patients (mean age: 16.3±7.58 years). Group\ud2 included 68 β-TT patients (mean age: 7.25±4.43 years). Group\ud3 consisted of 112 age- and sex-matched healthy controls (mean\udage: 9±4.7 years). Serum ferritin level was 2487±1103 (range:\ud661-5745) ng/mL in Group 1. In comparing the correlation\udbetween ferritin and lipid parameters, while a significantly\udnegative relationship was detected between ferritin and highdensity\udlipoprotein cholesterol (HDL-C) (p=0.000, r=-0.602), a\udsignificantly positive relationship was detected between ferritin\udand triglyceride (TG) levels (p=0.02) in TM patients. Serum lipid\udprofiles of the 3 groups are shown in Table 1

Serum Lipids in Turkish Patients with β-Thalassemia Major and β-Thalassemia Minor