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Post-hypoxia hypoxia-inducible factor (HIF)-1α activation plays a vital role in colorectal cancer (CRC) angiogenesis. Although glucose metabolism is induced in some cancer types via HIF-1α, the prognostic significance of HIF-1α in CRC and its correlation with 18 fluorinefluorodeoxyglucose ( 18 F-FDG) uptake in positron emission tomography (PET) remain controversial. This study aims to investigate the association between 18 F-FDG/PET parameters and HIF-1α expression in CRC.

molecular imaging and radionuclide therapy

Correlation of &lt;sup&gt;18&lt;/sup&gt;F-FDG/PET SUV&lt;sub&gt;max&lt;/sub&gt;, SUV&lt;sub&gt;mean&lt;/sub&gt;, MTV, and TLG with HIF-1α in Patients with Colorectal Cancer