English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

57 © Meandros Medical and Dental Journal, Published by Galenos Publishing House. This is article distributed under the terms of the Creative Commons Attribution NonCommercial 4.0 International Licence (CC BY-NC 4.0). Meandros Med Dent J 2019;20:57-63 Öz Amaç: Yüksek manyetik alan yaygın olarak biyolojik dokular için zararsız kabul edilse de, biyolojik etkileri konusunda fikir birliği yoktur. Bu çalışma, basit ve yaygın olarak kabul gören Allium testini kullanarak biyolojik dokulardaki manyetik alanın muhtemel genetik hasarlarını araştırmayı amaçlamaktadır. Gereç ve Yöntemler: Aynı büyüklükte sağlıklı Allium cepa (soğan) bitkileri 0, 8, 24, 72 saat 0,5 Tesla manyetik alana maruz bırakılan dört grupta incelendi. Maruziyet sonrası Allium testi yapılmış ve her grup için en az 4.000 hücre incelenmiştir. Bu hücrelerde gözlemlenen kromozom anormallikleri analiz edildi ve fotoğraflandı. Bulgular: Manyetik alan uygulaması, mitotik aktiviteyi olumsuz etkiledi. Kromozomal sapmalar, manyetik alana maruz kalma sürelerine oranla arttı. En sık görülen sapmalar C-metafaz, yapışkanlık (stickiness), geri kalmış kromozom (lagging chromosome), anafaz köprüsü (anaphase bridge), mikronükleus (micronucleus), düzensiz anafaz (irregular anaphase) ve kutup sapması (polar deviation) oldu. Grup Objective: Although the high magnetic field is commonly accepted as harmless for biological tissues, there is no consensus about its biological effects. This study aims to investigate probable genetic damages of magnetic field on biological tissues using a simple and widely accepted method, Allium test. Materials­and­Methods:­The same sized healthy Allium cepa (onion) plants were exposed to 0.5 Tesla magnetic field for 0, 8, 24 and 72 hours as groups of four. Allium test was applied and at least 4.000 cells were counted for each group. Observed chromosomal aberrations were analyzed and photographed. Results: Magnetic field application adversely affected the mitotic activity in the experiment group compared to the control. The chromosomal aberrations increased in proportion to increased magnetic field exposure times. The most encountered aberrations were C-metaphase, stickiness, lagging chromosome, anaphase bridge, micronucleus, irregular anaphase, and polar deviation. The group comparisons showed statistically significant differences between the control group and 8, 24 and 72 hour magnetic field exposure groups. Conclusion: This study has shown potential genotoxic and mutagenic effects of high magnetic field on Allium cepa root tip cells using Allium test. Although there is a need for more studies, the data in the study show that the strong magnetic field leads to chromosomal disorders. ORCID ID: orcid.org/0000-0003-4967-2740 Ad­dress­for­Cor­ res­pon­den­ce/Ya­zış­ma­Ad­ re­si: Handan Kayhan MD, Gazi University Faculty of Medicine, Department of Adult Hematology, Ankara, Turkey Phone : +90 536 439 25 99 E-mail : kayhanhandan@gmail.com Received/Geliş­Ta­rihi : 29.03.2017 Accepted/Ka­bul­Ta­ri­hi : 30.11.2017 Anah­tar­Ke­li­me­ler Manyetik alan, metafaz, mutajenik etkiler, Allium testi, Allium cepa

Investigation of Potential Genotoxic Effects of Magnetic Field Used in Imaging