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For every new public health intervention tool, whether it be antiretroviral drugs for human immunodeficiency virus, bed nets for malaria, or vaccines for rotavirus, there is, and should be, a public debate about whether the benefits of the tool are worth the cost and disruption that will accompany its implementation. The World Health Organization (WHO), as the United Nations agency with primary responsibility for international health policy, norms, and standards, is often criticized for moving too slowly or, rarely, too quickly in providing recommendations about new tools. With regard to Xpert MTB/RIF, the new, rapid, molecular test for tuberculosis and rifampin resistance, we think WHO has got it just about right, moving quickly with an evidence-based policy decision allowing the test's rapid uptake.

Transforming TB Diagnosis: Can Patients and Control Programs Afford to Wait?