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Infection with  Leptospira  spp. is common in Réunion, a tropical island in the Indian Ocean. However, respiratory coinfections between strains of  Leptospira  spp. and other microorganisms are rarely described. Here, we describe the first reported case of coinfection between  Leptospira  spp. and  Chlamydia pneumoniae , responsible for refractory acute respiratory distress syndrome requiring extracorporeal membrane oxygenation with a favorable outcome. In a case of leptospirosis with severe respiratory illness, testing for respiratory coinfection, especially with atypical pathogens, could explain the seriousness of the clinical condition and lead to specific treatment.

the american journal of tropical medicine and hygiene

Case Report: Refractory Acute Respiratory Distress Syndrome Supported by Extracorporeal Membrane Oxygenation due to Coinfection with Chlamydia pneumoniae and Leptospirosis in Reunion Island